Stem Cell Lab
It's Our Time
"Watch this dynamic five-minute video
detailing the striking statistics of the
progress and promise of cancer research.
"It's Our Time" was first presented at the
Opening Ceremony of the AACR 101st
Annual Meeting 2010."
Purdue to pursue development of anticancer therapeutics.
I have found Ixchel Scientific with a mission to eliminate metastatic cancer.
I can be reached at jkirshner at ixchelsci dot com.
|Tumors are formed when quescent cancer stem cells receive signals from the microenvironment to start differentiating and proliferating. One model describing this process suggests that this happens during asymetric self-renewal where one daughter cell differentiates into a tumor projenitor and the other maintains its stem cell phenotype. When the patient receives anti-cancer therapy, the tumor cells are killed, however, cancer stem cells are resistant to most currently used treatments, and thus, these cells remain and contribute to tumor relapse. Therefore, the cycle of tumorigenesis persists, and will persist until we design therapies which can eliminate cancer stem cells.|